{"id":110176,"date":"2026-04-08T05:06:50","date_gmt":"2026-04-08T05:06:50","guid":{"rendered":"http:\/\/eb28bd5bd5dfc5fa75d0e1404d9b771f"},"modified":"2026-04-08T05:06:50","modified_gmt":"2026-04-08T05:06:50","slug":"ni-vitaminas-ni-suplementos-este-antidepresivo-es-el-que-ha","status":"publish","type":"post","link":"https:\/\/sarmiento24h.com\/?p=110176","title":{"rendered":"Ni vitaminas ni suplementos: este antidepresivo es el que ha…"},"content":{"rendered":"

<\/p>\n

\n<\/p>\n
\n\"Archivo<\/div>\n


\n<\/p>\n

\nArchivo – Mujer con dolor de cabeza.<\/summary>\n

– ISTOCK – Archivo<\/figcaption><\/div>\n

\n<\/div>\n

<\/p>\n

   MADRID, 6 Abr. (EUROPA PRESS) – <\/p>\n

A pesar de que la fase aguda de la pandemia de COVID-19 qued\u00f3 atr\u00e1s, millones de personas en todo el mundo contin\u00faan lidiando con s\u00edntomas persistentes que afectan de forma significativa a su calidad de vida. Entre ellos, la fatiga prolongada se ha convertido en uno de los m\u00e1s incapacitantes y dif\u00edciles de tratar.<\/p>\n

    En este contexto, la comunidad cient\u00edfica sigue explorando posibles tratamientos que ayuden a mejorar el bienestar de estos pacientes. Nuevos ensayos cl\u00ednicos est\u00e1n empezando a arrojar resultados prometedores sobre f\u00e1rmacos ya conocidos que podr\u00edan tener un impacto inesperado en este problema de salud.<\/p>\n

UN ENSAYO CON CASI 400 PACIENTES EN 22 CENTROS<\/h2>\n

   Un equipo de investigaci\u00f3n global, codirigido por la Universidad McMaster (Canad\u00e1), ha identificado uno de los primeros medicamentos que ha demostrado reducir significativamente la fatiga en personas que viven con COVID persistente, un gran avance para millones de personas que a\u00fan luchan contra s\u00edntomas persistentes a\u00f1os despu\u00e9s del inicio de la pandemia.<\/p>\n

   El ensayo cl\u00ednico aleatorizado revel\u00f3 que el antidepresivo fluvoxamina reduce significativamente la fatiga persistente asociada a la COVID-19,<\/a> uno de los s\u00edntomas m\u00e1s debilitantes y persistentes de la enfermedad, mientras que el f\u00e1rmaco para la diabetes metformina no mostr\u00f3 ning\u00fan beneficio. <\/p>\n

LA FLUVOXAMINA MUESTRA MEJORAS EN FATIGA Y CALIDAD DE VIDA<\/h2>\n

Los pacientes que tomaron fluvoxamina informaron una mejora constante en la fatiga y en la calidad de vida durante 60 a 90 d\u00edas, con menos efectos secundarios que quienes recibieron placebo. Los hallazgos se publican en ‘Annals of Internal Medicine’.<\/a><\/p>\n

   Los investigadores evaluaron la eficacia de la fluvoxamina y la metformina para la fatiga persistente por COVID-19 en 399 personas en 22 centros ambulatorios de Brasil entre octubre de 2023 y febrero de 2025. Los participantes elegibles hab\u00edan experimentado fatiga durante al menos 90 d\u00edas despu\u00e9s de la infecci\u00f3n y fueron asignados a fluvoxamina, metformina o un placebo durante 60 d\u00edas. <\/p>\n

Los investigadores midieron los cambios utilizando una escala est\u00e1ndar de gravedad de la fatiga.<\/strong> La fluvoxamina produjo una reducci\u00f3n significativa de la fatiga al d\u00eda 60, con una mejora continua al d\u00eda 90, y tambi\u00e9n mejor\u00f3 la calidad de vida general. La metformina no mostr\u00f3 ning\u00fan efecto significativo.<\/p>\n

LA METFORMINA NO MOSTR\u00d3 BENEFICIOS EN LOS PACIENTES<\/h2>\n

    Si bien todos los tratamientos fueron generalmente seguros, la fluvoxamina present\u00f3 menos eventos adversos reportados. Los autores concluyen que la fluvoxamina podr\u00eda ofrecer una opci\u00f3n de tratamiento viable para la fatiga persistente por COVID-19, aunque se desconocen los efectos a largo plazo.<\/p>\n

Sin embargo, una limitaci\u00f3n importante del estudio fue la ausencia de evaluaci\u00f3n de antecedentes de depresi\u00f3n. Por lo tanto, no se puede determinar si el efecto del tratamiento se debi\u00f3 a un efecto directo sobre la fatiga persistente por COVID-19 o a un efecto sobre la depresi\u00f3n basal. <\/p>\n","protected":false},"excerpt":{"rendered":"

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