{"id":394926,"date":"2026-08-24T13:09:59","date_gmt":"2026-08-24T13:09:59","guid":{"rendered":"http:\/\/6a8760362343cb123e52f5f9"},"modified":"2026-08-24T13:09:59","modified_gmt":"2026-08-24T13:09:59","slug":"el-orden-oculto-detras-del-aparente-caos-del-cerebro-bajo-psilocibina","status":"publish","type":"post","link":"https:\/\/sarmiento24h.com\/?p=394926","title":{"rendered":"El orden oculto detr\u00e1s del aparente caos del cerebro bajo psilocibina"},"content":{"rendered":"<p>Los cient\u00edficos describen el cerebro bajo los efectos de psicod\u00e9licos como desincronizado y entr\u00f3picamente desordenado. Estudios de neuroimagen muestran que estas sustancias debilitan la organizaci\u00f3n habitual de las redes neuronales y aumentan la diversidad e imprevisibilidad de sus se\u00f1ales. Esa mayor diversidad se ha relacionado con el car\u00e1cter extra\u00f1o, aleatorio y a veces memorable de los \u201cviajes\u201d psicod\u00e9licos.<\/p>\n<p>Pero uno de los mayores estudios hasta ahora de neuroimagen sobre los efectos agudos de la <a href=\"https:\/\/es.wired.com\/articulos\/dos-pasos-adelante-uno-atras-en-la-investigacion-de-la-psilocibina-terapeutica\">psilocibina<\/a> acaba de encontrar una aparente contradicci\u00f3n. Detr\u00e1s de ese desorden hay un orden oculto. La psilocibina, en efecto, diluye algunas de las fronteras dentro del cerebro, pero al mismo tiempo hace m\u00e1s distinguible aquello que la persona vive en ese momento.<\/p>\n<hr>\n<div class=\"ContentCardEmbedWrapper-hkvhYu kMYDit content-card-embed content-card-embed--stacked\" data-testid=\"ContentCardEmbedWrapper\" readability=\"19.853873239437\">\n<div class=\"ContentCardEmbedImage-bqahne fjmzkP content-card-embed__image\" data-testid=\"ContentCardEmbedImage\"><span class=\"SpanWrapper-kFnjvc eKnjjD responsive-asset\"><picture class=\"ResponsiveImagePicture-jKunQM gjCCFj responsive-image\"><img decoding=\"async\" alt=\"Una ilustraci\u00f3n de un hongo alucin\u00f3geno coloreado con acuarela.\" loading=\"lazy\" class=\"ResponsiveImageContainer-dkeESL cQPiWi responsive-image__image\" srcset=\"https:\/\/media.es.wired.com\/photos\/6a763dddc28c5671b806c182\/master\/w_120,c_limit\/2224797854 120w, https:\/\/media.es.wired.com\/photos\/6a763dddc28c5671b806c182\/master\/w_240,c_limit\/2224797854 240w, https:\/\/media.es.wired.com\/photos\/6a763dddc28c5671b806c182\/master\/w_320,c_limit\/2224797854 320w, https:\/\/media.es.wired.com\/photos\/6a763dddc28c5671b806c182\/master\/w_640,c_limit\/2224797854 640w, https:\/\/media.es.wired.com\/photos\/6a763dddc28c5671b806c182\/master\/w_768,c_limit\/2224797854 768w\" sizes=\"100vw\" src=\"https:\/\/media.es.wired.com\/photos\/6a763dddc28c5671b806c182\/master\/w_775%2Cc_limit\/2224797854\"><\/picture><\/span><\/div>\n<div class=\"ContentCardEmbedInfo-buyHWH gWLOee\" readability=\"20.799295774648\">\n<div class=\"BaseText-fEwdHD ContentCardEmbedHed-kDKGDs iUENtL dlHXUJ content-card-embed__hed\" data-testid=\"ContentCardEmbedHed\"><a class=\"BaseLink-haTOKm ContentCardEmbedHedLink-iBZsco ILkR hhUFQU content-card-embed__hed-link link\" href=\"https:\/\/es.wired.com\/articulos\/hongo-que-te-hace-ver-gente-diminuta-lanmaoa-asiatica\" data-testid=\"ContentCardEmbedHedLink\">El extra\u00f1o hongo que te hace ver gente diminuta y el misterio qu\u00edmico detr\u00e1s de los duendes asi\u00e1ticos<\/a><\/div>\n<p>Un equipo de investigadores secuenci\u00f3 el ADN de <em>Lanmaoa asiatica<\/em> en busca de la clave detr\u00e1s de sus alucinaciones liliputienses. Todo apunta a una mol\u00e9cula totalmente in\u00e9dita.<\/p>\n<\/div>\n<\/div>\n<hr>\n<p>El estudio, publicado este mes en <a href=\"https:\/\/www.nature.com\/articles\/s41586-026-10910-z\"><em>Nature<\/em><\/a>, encontr\u00f3 que cuanto m\u00e1s intensa era la experiencia con psilocibina, con mayor claridad pod\u00eda reconocerse en las se\u00f1ales del cerebro si una persona descansaba, meditaba, o participaba en alguna actividad recreacional. En lugar de confundirse en medio de un \u201cviaje\u201d cada vez m\u00e1s impredecible, cada contexto dejaba una huella m\u00e1s definida.<\/p>\n<p>Ese orden est\u00e1 lejos de existir solo en las pantallas de los investigadores. Las personas que lo mostraban con mayor fuerza tambi\u00e9n tend\u00edan a describir experiencias m\u00e1s intensas de unidad, inmersi\u00f3n y disoluci\u00f3n de la frontera entre ellas mismas y el mundo que las rodeaba.<\/p>\n<p>\u201cBajo los <a href=\"https:\/\/es.wired.com\/articulos\/cientificos-descubren-que-los-hongos-alucinogenos-generan-psilocibina-mediante-dos-rutas-bioquimicas-distintas\">efectos de la psilocibina<\/a>, las redes neuronales que nos ayudan a procesar nuestro mundo interior y el mundo que nos rodea se volvieron menos diferenciadas, pero se reorganizaron en patrones que reflejaban las experiencias de las personas\u201d, explic\u00f3 Devon Stoliker, autor principal del estudio e investigador de la Facultad de Ciencias Psicol\u00f3gicas de la Universidad de Monash (en Australia).<\/p>\n<h2>C\u00f3mo encontraron el orden oculto<\/h2>\n<p>Para llegar a esa conclusi\u00f3n, los investigadores reclutaron a 62 adultos sanos pr\u00e1cticamente sin experiencia previa con psicod\u00e9licos. Primero registraron sus cerebros sin la sustancia y luego al administrarles 19 miligramos de psilocibina en una c\u00e1psula oral. Usaron resonancia magn\u00e9tica funcional y electroencefalograf\u00eda mientras los participantes descansaban, meditaban, escuchaban m\u00fasica o ve\u00edan una pel\u00edcula.<\/p>\n<p>Despu\u00e9s recurrieron a inteligencia artificial para seguir, momento a momento, los cambios en 332 regiones del cerebro, en vez de condensar varios minutos de informaci\u00f3n en un promedio. El sistema transform\u00f3 esos cambios en trayectorias y aprendi\u00f3 a reconocer cu\u00e1les correspond\u00edan al descanso, la meditaci\u00f3n, la m\u00fasica o la pel\u00edcula.<\/p>\n<p>\u201cMostramos que la psilocibina reorganiza <a href=\"https:\/\/es.wired.com\/articulos\/cerebro-sigue-aprendiendo-y-procesando-informacion-aun-bajo-anestesia-general\">la actividad cerebral<\/a> en patrones estructurados y sensibles al contexto que co-var\u00edan con la calidad de la experiencia subjetiva, revelando un orden latente que no se detecta con las medidas promediadas en el tiempo\u201d, escribieron los autores.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Los cient\u00edficos describen el cerebro bajo los&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":394927,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[46],"tags":[],"class_list":["post-394926","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tecnologia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - 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