{"id":461654,"date":"2026-10-01T20:17:02","date_gmt":"2026-10-01T20:17:02","guid":{"rendered":"http:\/\/6abea05008e4d7a798fd046d"},"modified":"2026-10-01T20:17:02","modified_gmt":"2026-10-01T20:17:02","slug":"esta-empresa-quiere-editar-embriones-y-asegura-que-es-un-imperativo-moral","status":"publish","type":"post","link":"https:\/\/sarmiento24h.com\/?p=461654","title":{"rendered":"Esta empresa quiere editar embriones y asegura que es \u00abun imperativo moral\u00bb"},"content":{"rendered":"<p>Cuando el cient\u00edfico chino He Jiankui anunci\u00f3 en 2018 que hab\u00eda creado los primeros beb\u00e9s con genes modificados, el experimento fue condenado por considerarse imprudente y prematuro. He termin\u00f3 en prisi\u00f3n.<\/p>\n<p>Pero eso no ha frenado el impulso a favor de los <a href=\"https:\/\/es.wired.com\/articulos\/logran-editar-con-precision-el-adn-de-embriones-humanos-acercando-la-posibilidad-de-bebes-modificados-geneticamente\">embriones humanos modificados<\/a> gen\u00e9ticamente, y la emprendedora biotecnol\u00f3gica Cathy Tie sostiene que hacerlo no solo es urgente, sino que es un \u00abimperativo moral\u00bb.<\/p>\n<p>Tie, de 30 a\u00f1os, es la fundadora de Origin Genomics, una empresa que se puso en marcha en marzo con el objetivo de llevar embriones modificados gen\u00e9ticamente a las cl\u00ednicas de <a href=\"https:\/\/es.wired.com\/articulos\/el-adn-de-bebes-concebidos-in-vitro-tiene-una-peculiar-firma-genetica\">fecundaci\u00f3n in vitro.<\/a> En un nuevo <a data-offer-url=\"https:\/\/www.cell.com\/trends\/genetics\/abstract\/S0168-9525(26)00218-0\" class=\"external-link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/www.cell.com\/trends\/genetics\/abstract\/S0168-9525(26)00218-0&quot;}\" href=\"https:\/\/www.cell.com\/trends\/genetics\/abstract\/S0168-9525(26)00218-0\" rel=\"nofollow noopener\" target=\"_blank\">art\u00edculo<\/a> publicado en la revista <em>Trends in Genetics<\/em>, aboga por la financiaci\u00f3n p\u00fablica y nuevas v\u00edas normativas para impulsar los beb\u00e9s modificados gen\u00e9ticamente y, en \u00faltima instancia, pasar a su uso cl\u00ednico.<\/p>\n<p>Sin embargo, persisten las dudas sobre qu\u00e9 pruebas necesitar\u00e1n los investigadores para determinar si los embriones editados son lo suficientemente seguros como para intentar un embarazo humano, y qu\u00e9 riesgos podr\u00edan suponer para los reci\u00e9n nacidos.<\/p>\n<p>\u00abHay casos que sirven de advertencia: primeros ensayos en humanos en los que no hubo ninguna se\u00f1al de alarma y, aun as\u00ed, algunas personas fallecieron\u00bb, afirma Hank Greely, profesor de Derecho y director del Centro de Derecho y Biociencias de la Universidad de Stanford.<\/p>\n<div class=\"ContentCardEmbedWrapper-hkvhYu kMYDit content-card-embed content-card-embed--stacked\" data-testid=\"ContentCardEmbedWrapper\" readability=\"24.543103448276\">\n<div class=\"ContentCardEmbedImage-bqahne fjmzkP content-card-embed__image\" data-testid=\"ContentCardEmbedImage\"><span class=\"SpanWrapper-kFnjvc eKnjjD responsive-asset\"><picture class=\"ResponsiveImagePicture-jKunQM gjCCFj responsive-image\"><img decoding=\"async\" alt=\"ADN de beb\u00e9s\" loading=\"lazy\" class=\"ResponsiveImageContainer-dkeESL cQPiWi responsive-image__image\" srcset=\"https:\/\/media.es.wired.com\/photos\/6abc2f4a8ab6a856a8629041\/master\/w_120,c_limit\/beb%C3%A9s%20in%20vitro%20gen%C3%A9tica%20924297554.jpg 120w, https:\/\/media.es.wired.com\/photos\/6abc2f4a8ab6a856a8629041\/master\/w_240,c_limit\/beb%C3%A9s%20in%20vitro%20gen%C3%A9tica%20924297554.jpg 240w, https:\/\/media.es.wired.com\/photos\/6abc2f4a8ab6a856a8629041\/master\/w_320,c_limit\/beb%C3%A9s%20in%20vitro%20gen%C3%A9tica%20924297554.jpg 320w, https:\/\/media.es.wired.com\/photos\/6abc2f4a8ab6a856a8629041\/master\/w_640,c_limit\/beb%C3%A9s%20in%20vitro%20gen%C3%A9tica%20924297554.jpg 640w, https:\/\/media.es.wired.com\/photos\/6abc2f4a8ab6a856a8629041\/master\/w_768,c_limit\/beb%C3%A9s%20in%20vitro%20gen%C3%A9tica%20924297554.jpg 768w\" sizes=\"100vw\" src=\"https:\/\/media.es.wired.com\/photos\/6abc2f4a8ab6a856a8629041\/master\/w_775%2Cc_limit\/beb%25C3%25A9s%2520in%2520vitro%2520gen%25C3%25A9tica%2520924297554.jpg\"><\/picture><\/span><\/div>\n<div class=\"ContentCardEmbedInfo-buyHWH gWLOee\" readability=\"26.431034482759\">\n<div class=\"BaseText-fEwdHD ContentCardEmbedHed-kDKGDs iUENtL dlHXUJ content-card-embed__hed\" data-testid=\"ContentCardEmbedHed\"><a class=\"BaseLink-haTOKm ContentCardEmbedHedLink-iBZsco ILkR hhUFQU content-card-embed__hed-link link\" href=\"https:\/\/es.wired.com\/articulos\/el-adn-de-bebes-concebidos-in-vitro-tiene-una-peculiar-firma-genetica\" data-testid=\"ContentCardEmbedHedLink\">El ADN de beb\u00e9s concebidos in vitro tiene una peculiar firma gen\u00e9tica<\/a><\/div>\n<p>Un estudio identific\u00f3 una mayor cantidad y distribuci\u00f3n diferenciada de genes LINE-1 en ni\u00f1os concebidos mediante fertilizaci\u00f3n <em>in vitro<\/em>, aunque los resultados no demuestran que estos cambios provoquen enfermedades.<\/p>\n<\/div>\n<\/div>\n<h2>Qu\u00e9 sabemos de la edici\u00f3n gen\u00e9tica<\/h2>\n<p>La denominada edici\u00f3n gen\u00e9tica de la l\u00ednea germinal consiste en modificar c\u00e9lulas implicadas en <a href=\"https:\/\/es.wired.com\/articulos\/los-espermatozoides-tienen-un-gps-y-cuando-se-enfrentan-a-microgravedad-este-falla-un-problema-para-el-futuro-espacial\">la reproducci\u00f3n humana<\/a>, como los embriones. Cualquier cambio realizado podr\u00eda transmitirse a futuras generaciones. Por ejemplo, eso podr\u00eda significar corregir de forma definitiva una mutaci\u00f3n gen\u00e9tica devastadora. Sin embargo, las modificaciones accidentales del ADN en otras zonas, conocidas como \u00abefectos fuera del objetivo\u00bb, podr\u00edan introducir nuevos riesgos para la salud que tambi\u00e9n podr\u00edan transmitirse. Esos altos riesgos son parte del motivo por el que docenas de pa\u00edses han prohibido la edici\u00f3n gen\u00e9tica de embriones humanos destinados al embarazo.<\/p>\n<p><strong>Las personas con riesgo de transmitir una enfermedad gen\u00e9tica a sus hijos pueden recurrir a la <a href=\"https:\/\/es.wired.com\/articulos\/como-un-medico-mexicano-esta-transformando-la-fertilizacion-in-vitro-con-ia\">fecundaci\u00f3n in vitro (FIV)<\/a> combinada con el cribado gen\u00e9tico para identificar embriones libres de la enfermedad antes de su transferencia al \u00fatero.<\/strong> Los detractores de la edici\u00f3n de embriones argumentan que las herramientas de cribado reducen considerablemente la necesidad de recurrir a ella. Seg\u00fan Greely, la edici\u00f3n gen\u00e9tica de embriones ayudar\u00eda a \u00abuna fracci\u00f3n de una fracci\u00f3n de una fracci\u00f3n\u00bb.<\/p>\n<p>El inconveniente del enfoque actual es que la FIV es ineficaz; puede resultar dif\u00edcil obtener embriones viables, incluso para personas sin riesgo de padecer una enfermedad hereditaria. Ian Watts y Cheyenne Ziegler se sometieron a tres ciclos de FIV en su intento de tener hijos que no portaran la variante gen\u00e9tica responsable de la enfermedad de Charcot-Marie-Tooth de Watts, un <a href=\"https:\/\/es.wired.com\/articulos\/las-enfermedades-neurologicas-ya-son-la-mayor-amenaza-para-la-salud-en-el-mundo\">trastorno neurol\u00f3gico degenerativo<\/a> que afecta a la motricidad fina y a la movilidad. En cualquier ciclo de FIV, es habitual que los \u00f3vulos no se fecunden, y los que lo hacen a menudo se detienen en su desarrollo o presentan anomal\u00edas cromos\u00f3micas. A\u00f1adir cribados adicionales para detectar enfermedades implica que algunos embriones viables tampoco superan el filtro.<\/p>\n<p>En el caso de Watts y Ziegler, tres ciclos de FIV han dado lugar a ocho embriones cromos\u00f3micamente normales, pero solo tres carecen de la variante de Watts. Es probable que esos tres embriones no sean suficientes para que la pareja tenga los tres o cuatro hijos que esperan tener alg\u00fan d\u00eda.<\/p>\n<p>\u00abActualmente, las opciones son no tener hijos o someterse a varios ciclos de FIV\u00bb, argumenta Watts, un ingeniero de 36 a\u00f1os de Long Beach, California. La edici\u00f3n gen\u00e9tica podr\u00eda ofrecer a personas como \u00e9l m\u00e1s oportunidades de formar una familia en el futuro. Tambi\u00e9n podr\u00eda ayudar a parejas en situaciones extremadamente raras en las que todos los embriones heredar\u00edan una mutaci\u00f3n causante de una enfermedad, como en el caso de parejas en las que ambos miembros tienen dos copias de una variante perjudicial.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cuando el cient\u00edfico chino He Jiankui anunci\u00f3&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":461655,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[46],"tags":[],"class_list":["post-461654","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tecnologia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - 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