{"id":493857,"date":"2026-10-19T19:59:29","date_gmt":"2026-10-19T19:59:29","guid":{"rendered":"http:\/\/6ad64d90e439b20ef0b11c95"},"modified":"2026-10-19T19:59:29","modified_gmt":"2026-10-19T19:59:29","slug":"este-hongo-mortal-que-circula-en-hospitales-contaminados-esta-ganando-resistencia-frente-a-nuestro-arsenal-antifungico","status":"publish","type":"post","link":"https:\/\/sarmiento24h.com\/?p=493857","title":{"rendered":"Este hongo mortal que circula en hospitales contaminados est\u00e1 ganando resistencia frente a nuestro arsenal antif\u00fangico"},"content":{"rendered":"<p>Desde hace a\u00f1os, los hospitales libran una batalla contra un hongo particularmente resistente, que encuentra en los hospitales y otros centros de atenci\u00f3n m\u00e9dica condiciones favorables para propagarse. Su presencia puede representar un peligro mortal para los pacientes inmunodeprimidos. Su nombre es <em>Candida auris<\/em>.<\/p>\n<p>Fue aislado en 2009, en Jap\u00f3n, y desde entonces el microorganismo ha sido detectado en numerosos pa\u00edses de todo el mundo. Incluso en 2023 Estados Unidos <a href=\"https:\/\/es.wired.com\/articulos\/alerta-por-el-aumento-de-infecciones-porandnbspcandida-auris-un-hongo-superresistente-y-potencialmente-mortal\">lanz\u00f3 una alerta ante el crecimiento de las infecciones<\/a>. Puede propagarse por contacto con personas o superficies contaminadas y permanecer en la piel sin causar s\u00edntomas. En condiciones normales, no es una amenaza grave para las personas, pero en pacientes vulnerables puede provocar infecciones de heridas, del torrente sangu\u00edneo y de otros \u00f3rganos, algunas de ellas potencialmente mort\u00edferas.<\/p>\n<p>Existen distintos linajes y cepas de la <em>C. auris<\/em>, algunos de ellos incluso han desarrollado mecanismos para resistir los tratamientos m\u00e9dicos. Por ello, se ha ganado el apodo del \u201c<a href=\"https:\/\/es.wired.com\/articulos\/descubren-en-singapur-la-cepa-de-candida-auris-mas-contagiosa-de-la-que-se-tenga-registro\">hongo superresistente<\/a>\u201d. Ahora, un reciente estudio acaba de encender de nuevo las alertas. Una de esas cepas, proveniente de Kenia, present\u00f3 resistencia a cuatro de los principales grupos de medicamentos antif\u00fangicos. Hasta ahora solo hab\u00eda otro caso documentado de resistencia simult\u00e1nea a estas cuatro familias.<\/p>\n<hr>\n<div class=\"ContentCardEmbedWrapper-hkvhYu kMYDit content-card-embed content-card-embed--stacked\" data-testid=\"ContentCardEmbedWrapper\" readability=\"22.178137651822\">\n<div class=\"ContentCardEmbedImage-bqahne fjmzkP content-card-embed__image\" data-testid=\"ContentCardEmbedImage\"><span class=\"SpanWrapper-kFnjvc eKnjjD responsive-asset\"><picture class=\"ResponsiveImagePicture-jKunQM gjCCFj responsive-image\"><img decoding=\"async\" alt=\"Ropa de segunda mano estilo vintage. \" loading=\"lazy\" class=\"ResponsiveImageContainer-dkeESL cQPiWi responsive-image__image\" srcset=\"https:\/\/media.es.wired.com\/photos\/6733b22286a7d812b5e23872\/master\/w_120,c_limit\/GettyImages-1417178020.jpg 120w, https:\/\/media.es.wired.com\/photos\/6733b22286a7d812b5e23872\/master\/w_240,c_limit\/GettyImages-1417178020.jpg 240w, https:\/\/media.es.wired.com\/photos\/6733b22286a7d812b5e23872\/master\/w_320,c_limit\/GettyImages-1417178020.jpg 320w, https:\/\/media.es.wired.com\/photos\/6733b22286a7d812b5e23872\/master\/w_640,c_limit\/GettyImages-1417178020.jpg 640w, https:\/\/media.es.wired.com\/photos\/6733b22286a7d812b5e23872\/master\/w_768,c_limit\/GettyImages-1417178020.jpg 768w\" sizes=\"100vw\" src=\"https:\/\/media.es.wired.com\/photos\/6733b22286a7d812b5e23872\/master\/w_775%2Cc_limit\/GettyImages-1417178020.jpg\"><\/picture><\/span><\/div>\n<div class=\"ContentCardEmbedInfo-buyHWH gWLOee\" readability=\"24.194331983806\">\n<div class=\"BaseText-fEwdHD ContentCardEmbedHed-kDKGDs iUENtL dlHXUJ content-card-embed__hed\" data-testid=\"ContentCardEmbedHed\"><a class=\"BaseLink-haTOKm ContentCardEmbedHedLink-iBZsco ILkR hhUFQU content-card-embed__hed-link link\" href=\"https:\/\/es.wired.com\/articulos\/acaros-hongos-y-germenes-la-ropa-usada-puede-ser-un-vehiculo-de-enfermedades\" data-testid=\"ContentCardEmbedHedLink\">\u00c1caros, hongos y g\u00e9rmenes: la ropa usada puede ser un veh\u00edculo de enfermedades<\/a><\/div>\n<p>La ropa <em>vintage<\/em> y de segunda mano, al igual que la nueva, contiene agentes pat\u00f3genos potenciales, por lo que es importante lavarla adecuadamente antes de pon\u00e9rtela.<\/p>\n<\/div>\n<\/div>\n<hr>\n<p>El estudio, publicado en la revista <a href=\"https:\/\/www.nature.com\/articles\/s41598-026-70653-9\"><em>Scientific Reports<\/em><\/a>, documenta hasta d\u00f3nde puede llegar la resistencia de este microorganismo. La cepa identificada en una paciente de 28 a\u00f1os en Kenia mostr\u00f3 resistencia a los azoles, las equinocandinas y los polienos, tres de las principales familias de medicamentos que integran el ya limitado arsenal antif\u00fangico de la medicina. Cada una ataca al hongo a trav\u00e9s de mecanismos distintos, pero esta variante presenta caracter\u00edsticas que le permiten resistir sus efectos.<\/p>\n<p>Esta cepa de la <em>Candida auris<\/em> tambi\u00e9n mostr\u00f3 resistencia a la flucitosina, un antif\u00fangico que act\u00faa interfiriendo con la producci\u00f3n de material gen\u00e9tico del microorganismo.<\/p>\n<p>La resistencia a los antif\u00fangicos es un proceso evolutivo similar al que ocurre con las <a href=\"https:\/\/es.wired.com\/articulos\/una-de-cada-tres-bacterias-que-infectan-a-ninos-ya-resiste-al-menos-un-antibiotico-comun\">bacterias resistentes a los antibi\u00f3ticos<\/a>. Los hongos pueden desarrollar mutaciones que les permiten sobrevivir a determinados medicamentos. Cuando son expuestos a estos tratamientos, los microorganismos susceptibles pueden desaparecer, mientras que los resistentes sobreviven y se reproducen, extendiendo estas caracter\u00edsticas a nuevas generaciones.<\/p>\n<p>En el caso de <em>Candida auris<\/em>, los investigadores identificaron alteraciones gen\u00e9ticas asociadas con distintos mecanismos de resistencia. Algunas modifican las estructuras celulares que atacan los medicamentos, mientras que otras pueden facilitar su expulsi\u00f3n del organismo. La combinaci\u00f3n de estos mecanismos podr\u00eda explicar c\u00f3mo una misma cepa consigue resistir tratamientos que act\u00faan de maneras diferentes.<\/p>\n<p>Por ahora, el caso de Kenia no implica que las cepas de <em>C. auris<\/em> resistentes a todos estos medicamentos est\u00e9n propag\u00e1ndose por el mundo. Sin embargo, el hongo, en sus distintas varientes, contin\u00faa expandi\u00e9ndose. Seg\u00fan los <a href=\"https:\/\/www.cdc.gov\/candida-auris\/tracking-c-auris\/?CDC_AA_refVal=.html&amp;utm_source=chatgpt.com\">datos del Centros para el Control y la Prevenci\u00f3n de Enfermedades (CDC)<\/a>, solo en Estados Unidos los casos cl\u00ednicos reportados pasaron de 2,915 en 2022 a 6,304 en 2024.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Desde hace a\u00f1os, los hospitales libran una&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":493858,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[46],"tags":[],"class_list":["post-493857","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tecnologia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - 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