{"id":495828,"date":"2026-10-20T21:37:32","date_gmt":"2026-10-20T21:37:32","guid":{"rendered":"http:\/\/6ad79cb25db16267f6bbd6f4"},"modified":"2026-10-20T21:37:32","modified_gmt":"2026-10-20T21:37:32","slug":"la-unam-desarrolla-nanovehiculos-que-trasladan-medicamentos-al-cerebro-para-combatir-el-cancer-y-otras-enfermedades","status":"publish","type":"post","link":"https:\/\/sarmiento24h.com\/?p=495828","title":{"rendered":"La UNAM desarrolla nanoveh\u00edculos que trasladan medicamentos al cerebro para combatir el c\u00e1ncer y otras enfermedades"},"content":{"rendered":"<p>Investigadores de la Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), en Baja California, desarrollan una tecnolog\u00eda que podr\u00eda facilitar el diagn\u00f3stico y tratamiento de diversas enfermedades neurol\u00f3gicas y neurodegenerativas, como el Parkinson, el Alzheimer, la epilepsia y la esclerosis m\u00faltiple, as\u00ed como de algunos tipos de c\u00e1ncer.<\/p>\n<p>El proyecto, liderado por cient\u00edficos del Centro de Nanociencias y Nanotecnolog\u00eda (CNyN) de la UNAM, campus Ensenada, se enfoca en convertir virus de plantas y bacterias en veh\u00edculos org\u00e1nicos de entre 20 y 60 nan\u00f3metros, capaces de transportar y depositar sustancias de manera focalizada en tumores o tejidos espec\u00edficos del cuerpo humano. Seg\u00fan los especialistas, <strong>estos nanoveh\u00edculos abrir\u00edan nuevas posibilidades para implementar t\u00e9cnicas de teragn\u00f3stico<\/strong>, un m\u00e9todo que combina el diagn\u00f3stico y el tratamiento para localizar c\u00e9lulas enfermas y actuar sobre ellas de manera simult\u00e1nea.<\/p>\n<p>Uno de los principales obst\u00e1culos de la <a href=\"https:\/\/es.wired.com\/articulos\/congelar-el-cerebro-para-despertarlo-en-el-futuro-algunos-medicos-comienzan-a-creer-en-superar-la-muerte\">neuromedicina<\/a> es superar la barrera hematoencef\u00e1lica, una estructura que impide el ingreso al cerebro de sustancias potencialmente da\u00f1inas, pero que tambi\u00e9n dificulta la entrada de medicamentos.<\/p>\n<hr>\n<div class=\"ContentCardEmbedWrapper-hkvhYu kMYDit content-card-embed content-card-embed--stacked\" data-testid=\"ContentCardEmbedWrapper\" readability=\"20.648496240602\">\n<div class=\"ContentCardEmbedImage-bqahne fjmzkP content-card-embed__image\" data-testid=\"ContentCardEmbedImage\"><span class=\"SpanWrapper-kFnjvc eKnjjD responsive-asset\"><picture class=\"ResponsiveImagePicture-jKunQM gjCCFj responsive-image\"><img decoding=\"async\" alt=\"Parkinson veneno de abeja\" loading=\"lazy\" class=\"ResponsiveImageContainer-dkeESL cQPiWi responsive-image__image\" srcset=\"https:\/\/media.es.wired.com\/photos\/6a624972baec16443ee715fe\/master\/w_120,c_limit\/abejas.jpg 120w, https:\/\/media.es.wired.com\/photos\/6a624972baec16443ee715fe\/master\/w_240,c_limit\/abejas.jpg 240w, https:\/\/media.es.wired.com\/photos\/6a624972baec16443ee715fe\/master\/w_320,c_limit\/abejas.jpg 320w, https:\/\/media.es.wired.com\/photos\/6a624972baec16443ee715fe\/master\/w_640,c_limit\/abejas.jpg 640w, https:\/\/media.es.wired.com\/photos\/6a624972baec16443ee715fe\/master\/w_768,c_limit\/abejas.jpg 768w\" sizes=\"100vw\" src=\"https:\/\/media.es.wired.com\/photos\/6a624972baec16443ee715fe\/master\/w_775%2Cc_limit\/abejas.jpg\"><\/picture><\/span><\/div>\n<div class=\"ContentCardEmbedInfo-buyHWH gWLOee\" readability=\"22.236842105263\">\n<div class=\"BaseText-fEwdHD ContentCardEmbedHed-kDKGDs iUENtL dlHXUJ content-card-embed__hed\" data-testid=\"ContentCardEmbedHed\"><a class=\"BaseLink-haTOKm ContentCardEmbedHedLink-iBZsco ILkR hhUFQU content-card-embed__hed-link link\" href=\"https:\/\/es.wired.com\/articulos\/ciencia-mexicana-confirma-que-el-veneno-de-abeja-puede-potenciar-el-tratamiento-para-el-parkinson\" data-testid=\"ContentCardEmbedHedLink\">Ciencia mexicana confirma que el veneno de abeja puede mejorar los tratamientos para el Parkinson<\/a><\/div>\n<p>Investigadores de la Universidad de Guadalajara documentaron c\u00f3mo el veneno de abeja, combinado con L-DOPA, mejor\u00f3 el movimiento y la memoria en ratones con Parkinson.<\/p>\n<\/div>\n<\/div>\n<hr>\n<p>\u201cPara protegerse de agentes externos, el cerebro cuenta con una barrera hematoencef\u00e1lica que permite que apenas entre el 0.2 y el 2% del f\u00e1rmaco administrado ingrese a dicho \u00f3rgano\u201d, se\u00f1al\u00f3 Rafael V\u00e1zquez Duhalt, investigador del CNyN.<\/p>\n<p>Actualmente, para garantizar que los tratamientos lleguen a los tejidos cerebrales afectados, se utilizan terapias sist\u00e9micas basadas en dosis altas. Sin embargo, al igual que ocurre con ciertos tipos de c\u00e1ncer, este enfoque puede <strong>reducir la eficiencia de los medicamentos y provocar efectos secundarios<\/strong>, debido a la exposici\u00f3n de \u00f3rganos sanos a sustancias potencialmente da\u00f1inas.<\/p>\n<p>El equipo de la UNAM busca resolver este problema mediante el desarrollo de nanopart\u00edculas fabricadas con virus de plantas y bacteri\u00f3fagos, es decir, virus que infectan bacterias, cuyas caracter\u00edsticas destacan por su inocuidad y biocompatibilidad con el ser humano. Rub\u00e9n Dar\u00edo Cadena, investigador del CNyN, explic\u00f3 que, para producir estos nanoveh\u00edculos, los especialistas aprovechan las propiedades naturales de las prote\u00ednas que recubren el material contenido en los virus y sustituyen el material gen\u00e9tico infeccioso por f\u00e1rmacos.<\/p>\n<p>\u201cMimetizamos lo que hacen naturalmente. Los virus son una caja de prote\u00ednas de escala nanom\u00e9trica con material gen\u00e9tico en su interior. Nosotros retiramos ese contenido infeccioso y lo reemplazamos con f\u00e1rmacos. El resultado es una part\u00edcula tipo virus (VLPs)\u201d, explic\u00f3. La capa de prote\u00ednas que la recubre y resguarda, llamada c\u00e1pside, protege la <a href=\"https:\/\/es.wired.com\/articulos\/una-molecula-podria-reactivar-las-defensas-naturales-del-cerebro-contra-el-alzheimer\">mol\u00e9cula terap\u00e9utica<\/a> y evita su degradaci\u00f3n, precis\u00f3 Cadena.<\/p>\n<p>Una de las caracter\u00edsticas m\u00e1s relevantes de esta tecnolog\u00eda es que, despu\u00e9s de fabricar las part\u00edculas, los investigadores emplean t\u00e9cnicas de bionanotecnolog\u00eda para modificar su superficie e incorporar mol\u00e9culas que la barrera hematoencef\u00e1lica reconoce, lo que favorece el ingreso de los nanoveh\u00edculos al cerebro.<\/p>\n<p>V\u00e1zquez Duhalt <a data-offer-url=\"https:\/\/unamglobal.unam.mx\/global_tv\/avanza-investigacion-para-llevar-medicamentos-al-cerebro-con-nanotecnologia\/?shem=dsdf,sharefoc,agadiscoversdl,,sh\/x\/discover\/m1\/4\" class=\"external-link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/unamglobal.unam.mx\/global_tv\/avanza-investigacion-para-llevar-medicamentos-al-cerebro-con-nanotecnologia\/?shem=dsdf,sharefoc,agadiscoversdl,,sh\/x\/discover\/m1\/4&quot;}\" href=\"https:\/\/unamglobal.unam.mx\/global_tv\/avanza-investigacion-para-llevar-medicamentos-al-cerebro-con-nanotecnologia\/?shem=dsdf,sharefoc,agadiscoversdl,,sh\/x\/discover\/m1\/4\" rel=\"nofollow noopener\" target=\"_blank\">subray\u00f3<\/a> que \u201c<strong>esta tecnolog\u00eda abre la oportunidad de llevar el f\u00e1rmaco hasta alg\u00fan organelo, como la mitocondria, o sea, a la estructura en el interior de la c\u00e9lula.<\/strong> As\u00ed, en vez de tomar dosis enormes, las reducimos y dirigimos a donde hacen falta. Se trata de una medicina mucho m\u00e1s inteligente, y ya est\u00e1 en desarrollo\u201d.<\/p>\n<figure data-testid=\"IframeEmbed\" class=\"IframeEmbedWrapper-sc-fixZhC fJBrNq iframe-embed\"><\/figure>\n<h2>Una \u201cmedicina inteligente\u201d para combatir el c\u00e1ncer<\/h2>\n<p>Los investigadores universitarios sostienen que las propiedades de estas nanopart\u00edculas tambi\u00e9n podr\u00edan mejorar los tratamientos contra el c\u00e1ncer y facilitar el desarrollo de terapias para prevenir posibles reca\u00eddas.<\/p>\n<p>Kanchan Chauhan, jefa del Departamento de Bionanotecnolog\u00eda del CNyN, record\u00f3 que los tumores est\u00e1n formados por diferentes tipos de c\u00e9lulas que activan mecanismos para sobrevivir a los medicamentos. Este fen\u00f3meno favorece la persistencia de la enfermedad o su reaparici\u00f3n. Ante este problema, los cient\u00edficos proponen combinar distintas terapias en una misma nanopart\u00edcula para <a href=\"https:\/\/es.wired.com\/articulos\/nueva-terapia-contra-el-cancer-consiste-en-reprogramar-el-sistema-inmunitario-con-nanoparticulas-inteligentes\">combatir el c\u00e1ncer<\/a> con mayor eficacia.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Investigadores de la Universidad Nacional Aut\u00f3noma de&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":495829,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[46],"tags":[],"class_list":["post-495828","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tecnologia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - 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